Figure 1.

Study enrollment flow chart. High-risk conditions include stem cell and solid organ transplants, severe immunocompromise (leukemia/lymphoma, chemotherapy, other immune disorders, and long-term steroid use), critical illness (trauma, septicemia, necrotizing fasciitis, intracranial hemorrhage, and mechanical ventilation for ≥96 hours), mild-to- moderate immunocompromise (end-stage renal disease or hemodialysis, lupus, malignant solid tumors, diabetic ketoacidosis, and blood disorders), major surgery, and other conditions (pneumonia, chronic obstructive pulmonary disease, and human immunodeficiency virus infection). Abbreviations: HCUP, Health Care Utilization Project; IA, invasive aspergillosis; NIS, National Inpatient Sample.