Table 3:
Risk of Colectomy at 90 days and Postoperative Complications by Inter-quartile Ciclosporin Levels
| Ciclosporin Level (ng/mL) |
Colectomy | Complications* | |||||
|---|---|---|---|---|---|---|---|
| Odds Ratio | 95% Confidence Interval | P value | Odds Ratio | 95% Confidence Interval | P value | ||
| 1st Quartile | First (<177) | Ref. | Ref. | ||||
| Mean (<237) | Ref. | Ref. | |||||
| Peak (<347) | Ref. | Ref. | |||||
| 2nd Quartile | First (177–263) | 1.2 | 0.43–3.30 | 0.75 | 0.64 | 0.14–3.07 | 0.59 |
| Mean (237–277) | 1.3 | 0.46–3.65 | 0.62 | 0.3 | 0.06–1.4 | 0.13 | |
| Peak (347–418) | 1.3 | 0.46–3.65 | 0.62 | 0.3 | 0.06–1.4 | 0.13 | |
| 3rd Quartile | First (264–330) | 1.04 | 0.43–2.53 | 0.9 | 0.95 | 0.23–3.83 | 0.94 |
| Mean (278–354) | 0.89 | 0.37–2.16 | 0.8 | 0.6 | 0.14–2.48 | 0.47 | |
| Peak (419–490) | 1.5 | 0.62–3.68 | 0.37 | 0.48 | 0.11–2.0 | 0.3 | |
| 4th Quartile | First (>331) | 0.95 | 0.35–2.6 | 0.92 | 1.33 | 0.28–6.26 | 0.72 |
| Mean (>355) | 0.75 | 0.28–2.05 | 0.58 | 2.78 | 0.61–12.5 | 0.19 | |
| Peak (>490) | 0.87 | 0.32–2.4 | 0.79 | 0.75 | 0.13–4.2 | 0.75 | |
Postoperative complications analyzed in this study include: infections (pelvic infection, surgical wound infections, and presence of sepsis) and noninfectious complications (presence of thrombosis and rehospitalization).