Table 4:
Association Between Clinical Factors and Postoperative Complications
| Variable | No Complication n(%) n = 37 (79%) | Complication (n,%) n = 10 (21%) | P value |
|---|---|---|---|
| Age [mean in years (SD)] | 32 (12) | 33 (13) | 0.79 |
| Female gender [n (%)] | 12 (32.4) | 4 (40) | 0.66 |
| CRP [mean in mg/dL (SD)] | 34.7 (30) | 49 (54) | 0.44 |
| Albumin level [mean (SD)] | 3.8 (0.7) | 3.7 (0.7) | 0.75 |
| Active smoker [n (%)] | 1 (2.7) | 4 (40) | 0.002* |
| Deep colonic ulcers [n (%)] | 14 (37.8) | 2 (20) | 0.27 |
| Kidney injury [n (%)] | 8 (21.6) | 0 | 0.11 |
| aPrior anti-tumor necrosis factor agent use (Anti-TNF) [n (%)] | 2 (5.4) | 0 | 0.45 |
| aPrior use of immunomodulators [n (%)] | 27 (73) | 6 (60) | 0.43 |
| aPrior clostridium difficle infection [n (%)] | 3 (8.1) | 1 (10) | 0.85 |
| aPrior cytomegalovirus (CMV) infection [n (%)] | None | 3 (30) | 0.002* |
| Days on intravenous steroids before initiation of cyclosporine [mean in days, SD] | 4.59 (2.35) | 4.25 (2.49) | 0.70 |
a “Prior” refers to use of anti-TNF agents, immunomodulators, or infection with clostridium difficle or CMV at any time point before IV ciclosporin administration