Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Infiltration of inflamed tissues by CD4+ CTLs and CD8+ CTLs and the apoptosis of endothelial cells may contribute to this disease. Reactivation of CD4+ CTLs may require antigen presentation by activated B cells in tissue sites. Cell apoptosis and macrophage and fibroblast activation by cytokines secreted by cytotoxic T cells may together contribute to fibrosis.
