TABLE 3.
Minimal inhibition concentrations (MICs) of the tested antimicrobial drugs.
| Drug | Minimum inhibitory concentrations (μg/ml) |
||||||
| E.coli/pET28a | E.coli/pET28a-ybhF | E.coli△ybhF | E.coli△ybhS | E.coli△ybhR | E.coli △acrB | E.coli△acrB△ybhF | |
| Tetracycline | 1 | 2 | 0.5 | 1 | 0.5 | 0.25 | 0.125 |
| Oxytetracycline | 32 | 128 | 16 | 32 | 16 | 8 | 4 |
| Chlortetracycline | 64 | 64 | 1 | 64 | 1 | 0.125 | < 0.125 |
| Doxycycline | 32 | 32 | 1 | 32 | 1 | 0.125 | < 0.125 |
| Ethidium | 256 | 256 | 128 | 256 | 128 | 128 | 16 |
| Hoechst | 128 | 128 | 64 | 128 | 64 | 64 | 32 |
| Cefoperazone | 1 | 1 | 1 | 1 | 1 | 0.125 | 0.125 |
| Cefazolin | 64 | 64 | 32 | 64 | 64 | 32 | 32 |
| Streptomycin | > 256 | >256 | > 256 | >256 | > 256 | >256 | > 256 |
| Ampicillin | 8 | 8 | 8 | 8 | 8 | 4 | 4 |
| Roxithromycin | > 256 | >256 | > 256 | >256 | > 256 | >256 | > 256 |
| Chloramphenicol | 32 | 32 | 32 | 32 | 32 | 0.5 | 0.5 |
| Rifampicin | 16 | 16 | 16 | 16 | 16 | 8 | 8 |
| Norfloxacin | 2 | 2 | 2 | 2 | 2 | < 0.125 | <0.125 |
| Deoxycholate | > 256 | >256 | > 256 | >256 | > 256 | >256 | > 256 |
| Sodium cholate | > 256 | >256 | > 256 | >256 | > 256 | >256 | > 256 |
| Ofloxacin | 0.125 | 0.125 | 0.125 | 0.125 | 0.125 | < 0.125 | <0.125 |
| Doxorubicin | 4 | 4 | 4 | 4 | 4 | 4 | 1 |
| Daunorubicin | 64 | 64 | 64 | 64 | 64 | 1 | 1 |
| Acridine flavin | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 |
| Quinine | > 256 | >256 | > 256 | >256 | > 256 | 0.5 | 0.5 |