Figure 2.

Regulation of circEIF3I on PTC cell proliferation, migration and invasion. A and B. circEIF3I expression was significantly decreased or increased by transfection with sh-circEIF3I or oe-circEIF3I plasmids compared to negative control (NC) group. C. CCK8 assays showed that proliferation of PTC-1 and IHH4 cells was inhibited by circEIF3I depletion, and vice versa. D. Colony formation assay showed that circEIF3I depletion reduced the colony formation number, and vice versa. E and F. Transwell assay indicated that circEIF3I depletion suppressed migration and invasion, and vice versa. *P<0.05, **P<0.01 and ***P<0.001