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. 2020 Apr 1;10(4):1130–1139.

Figure 5.

Figure 5

KIF2A was targeted by miR-149. A. qRT-PCR showed that KIF2A was upregulated in PTC tissues compared to adjacent normal tissues. B. There was a reverse correlation between miR-149 and KIF2A, and a positive correlation between KIF2A and circEIF3I in PTC tissues. C. The predicted binding site with miR-149 and KIF2A-3’UTR-Mut sequence was shown. D. Luciferase reporter assay showed that miR-149 overexpression suppressed the activity of KIF2A-3’UTR-WT reporter. E and F. qRT-PCR and WB analysis showed that circEIF3I knockdown inhibited KIF2A expression. G and H. qRT-PCR and WB analysis showed that miR-149 overexpression inhibited KIF2A expression. **P<0.01 and ***P<0.001.