TABLE 1.

Lumbar and cranial time course of 99mTc‐DTPA signal (percentage of injected activity)

Group		1 Hour	4 Hours	20 Hours
5 mL	Lumbar	52.7 ± 7.9†	24.2 ± 8.6	5.7 ± 1.9
	Cranial	2.5 ± 2.7†	22.9 ± 12.2	33.5 ± 10.2
15 m	Lumbar	29.6 ± 2.7	9.0  ± 2.0	1.8 ± 0.8†
	Cranial	13.2 ± 5.2	37.7  ± 6.6	29.9 ± 4.0
30 mL	Lumbar	46.2 ± 11.4	20.6  ± 8.4	4.2 ± 2.3
	Cranial	8.6 ± 4.7	24.0  ± 5.8	24.8 ± 9.8
5 mL Vest	Lumbar	46.8 ± 7.8†	20.8 ± 11.9	4.3 ± 4.1
	Cranial	2.2 ± 2.2†	14.0 ± 8.8†	18.1 ± 14.4
5 mL Wrap	Lumbar	47.6 ± 7.1†	15.7 ± 3.4†	2.5 ± 1.3
	Cranial	9.8 ± 8.4	29.6 ± 14.5	22.3 ± 7.0

Time course of lumbar and cranial ^99mTc‐DTPA signal for each dosing group. Data are presented as percentage of injected activity measured at 1, 4, and 20 hours (mean ± SEM; n = 3). All subjects were imaged within 11% of the indicated post‐dosing time. Asterisks indicate statistically significant differences from the 5 mL alone condition.