Table 3.
Correlations between VDR expression of CRC and clinicopathologic factors
| Variable | VDR expression | P-value | ||
|---|---|---|---|---|
|
| ||||
| Total Cases (%) (n = 188) | Low No. (%) | High No. (%) | ||
| Gender | 0.944 | |||
| Male | 111 (59.0) | 64 (57.66) | 47 (42.34) | |
| Female | 77 (41.0) | 44 (57.14) | 33 (42.86) | |
| Age (yrs) | 0.064 | |||
| ≤ 60 | 54 (28.7) | 31 (57.41) | 23 (42.59) | |
| > 60 | 134 (71.3) | 57 (42.54) | 77 (57.46) | |
| Tumor location | 0.421 | |||
| Colon | 91 (48.4) | 55 (60.44) | 36 (39.56) | |
| Rectum | 97 (51.6) | 53 (54.64) | 44 (45.36) | |
| Size (cm) | 0.272 | |||
| ≤ 5 cm | 97 (51.6) | 52 (53.61) | 45 (46.39) | |
| > 5 cm | 91 (48.4) | 56 (61.54) | 35 (38.46) | |
| General type | 0.239 | |||
| Bulging type | 61 (32.4) | 30 (49.18) | 31 (50.82) | |
| Ulcer type | 121 (64.4) | 75 (61.98) | 46 (38.02) | |
| Mushroom type | 6 (3.2) | 3 (50.00) | 3 (50.00) | |
| Differentiation | 0.117 | |||
| High | 8 (4.3) | 2 (25.00) | 6 (75.00) | |
| Middle | 156 (83.0) | 90 (57.69) | 66 (42.31) | |
| Low | 24 (12.8) | 16 (66.67) | 8 (33.33) | |
| Invasion depth | 0.001 | |||
| T1-T2 | 46 (24.5) | 17 (36.96) | 29 (63.04) | |
| T3-T4 | 142 (75.5) | 91 (64.08) | 51 (35.92) | |
| Lymph node metastasis | 0.315 | |||
| N0 | 112 (59.6) | 61 (54.46) | 51 (45.54) | |
| N1-N3 | 76 (40.4) | 47 (61.84) | 29 (38.16) | |
| TNM Stage | 0.210 | |||
| I+II | 110 (58.5) | 59 (53.64) | 51 (46.36) | |
| III+IV | 78 (41.5) | 49 (62.82) | 29 (37.18) | |
P < 0.05 was considered significant.