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. 2020 Apr 15;12(4):1255–1266.

Figure 5.

Figure 5

Effects of ligustrazine or/and Paeonol on liver fibrosis markers, ECM major components and MMPs related protein and gene expression in HSC. A. Western blot analyses of α-SMA, Fibronectin, Procollagen, MMP-2, MMP-9, TIMP-1, TGF-β, Smad2/3, PDGF and BMP-2. B. RT-PCR analysis of α-SMA, Fibronectin, TGF-β and PDGF gene. 1: model group, 2: ligustrazine group (20 μM/L), 3: paeonol group (25 μM/L), 4: combined intervention group (Combined intervention with ligustrazine 20 μM/L and paeonol 25 μM/L). *, P<0.05, **, P<0.01 and ***, P<0.001 vs. model group.