Figure 6.

Predictive targets for HCC prognosis. A, B. The prognostic values of the PTTG1, CCNB1, CDK1, AURKA, UBE2C, and ZWINT genes were explored. The Kaplan-Meier plotter bioinformatics analysis platform was used. We found that with high-level expression gene PTTG1, patients had an unfavorable overall survival (OS) and progression-free survival (PFS) compared with corresponding low expression level group. Similarly, the results from the rest of genes CCNB1, CDK1, AURKA, UBE2C, and ZWINT were observed, which corresponded with PTTG1. The findings showed that the high expression levels of these six genes PTTG1, CCNB1, CDK1, AURKA, UBE2C, and ZWINT were associated with an unfavorable overall survival (OS) and progression-free survival (PFS) of HCC patients. Thereby, our data suggested that PTTG1, CCNB1, CDK1, AURKA, UBE2C, and ZWINT might function as potential targets for HCC prognosis in patients. HCC, hepatocellular carcinoma.