Table 2.

miRNA NGS data of total reads of averaged individual HD and MM samples of plasma and EV samples, analyzed in blood collected in either EDTA or Streck tubes.

Read set (average)	EDTA plasma	Streck plasma	EDTA EV	Streck EV
Control
Total reads	12 918 867	14 473 494	13 627 945	12 763 090
Too short reads	5 230 193	5 869 227	4 405 809	6 672 979
miRNA reads	1 308 356	828 325	7 390 907	3 990 079
miRNA + piRNA UMIs	504 231	288 253	1 399 170	387 321
% UMIs/reads	3.9	2.0	10.3	3.0
Median UMIs	42.5	42.0	5.4	4.0
MM patients
Total reads	17 902 408	15 079 146	13 323 562	15 583 441
Too short reads	7 157 874	6 205 271	5 231 919	8 248 732
miRNA reads	2 034 688	1 061 176	5 928 317	4 775 402
miRNA + piRNA UMIs	657 612	352 714	1 228 334	615 673
% UMIs/reads	3.7	2.3	9.2	4.0
Median UMIs	45.6	37.0	5.1	4.0