Table 5. In vitro permeability parameters of azelaic acid-loaded MEs through hairy abdominal and non-hairy ear skin guinea pig (Mean±SD, n=5) .

Formulation	Hairy Abdominal skin		Non-hairy ear skin
	J ss (mg/cm 2 .h)	P (mg/cm 2 )	J ss (mg/cm 2 .h)	P (mg/cm 2 )
Control	0.481±0.018	0.0069±0.0003	0.4968±0.018	0.006±0.0002
ME-1	1.43±0.17	0.0143±0.0017	0.92±0.04	0.009±0.0004
ME-2	0.896±0.071	0.0089±0.0007	2.12±0.29	0.021±0.002
ME-3	0.734±0.06	0.0073±0.0006	1.38±0.004	0.0138±0.00004
ME-4	0.826±0.07	0.0082±0.0007	1.32±0.78	0.0132±0.007
ME-5	1.076±0.30	0.0707±0.003	1.47±0.02	0.0147±0.0002
ME-6	0.847±0.26	0.0084±0.002	1.184±0.04	0.0118±0.0004
ME-7	0.611±0.29	0.0061±0.002	1.6±0.26	0.0160±0.002
ME-8	0.232±0.046	0.0023±0.0004	0.56±0.17	0.0056±0.001