Table 2. Evaluation of oxidative damage potentials of CuO-NPs .

Cells	Exposure concentration (µg/mL)	GSH (µmol /g protein)	MDA (µmol/g protein)	8-OHdG (µg/g protein)	PC (µg/g protein)
HepG2	NC	53 ± 1.2	0.32 ± 0.05	1.1 ± 0.12	6.6 ± 0.57
	5	38 ± 0.99*	0.41 ± 0.03	0.91 ± 0.22	6.1 ± 0.64
	10	38 ± 1.1*	0.44 ± 0.01	0.97 ± 0.09	6.9 ± 0.52
	15	40 ± 0.95*	0.43 ± 0.05	1.1 ± 0.11	6.4 ± 0.49
	25	36 ± 1.4*	0.42 ± 0.03	1.1 ± 0.12	7.3 ± 0.62
Caco-2	NC	41 ± 1.3*	0.35 ± 0.02	0.96 ± 0.09	8.2 ± 0.35
	5	30 ± 0.86*	0.36 ± 0.05	0.99 ± 0.08	8.4 ± 0.35
	10	31 ± 0.63*	0.52 ± 0.04*	0.95 ± 0.15	8.1 ± 0.78
	15	27 ± 0.73*	0.51 ± 0.02*	0.96 ± 0.07	7.6 ± 0.48
	25	22 ± 0.57*	0.52 ± 0.04*	0.94 ± 0.09	8.4 ± 0.72

Note. The protein amount calculated for 4x10⁴ cells in every assay. The results were expressed as ± SD. * P ≤ 0.05 was significance. NC refers to negative control (unexposed cells).