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. 2020 Apr 23;11:243. doi: 10.3389/fphar.2020.00243

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Copyright © 2020 Jorge, Harada, Silva, Campos, Moreli, Shimamoto, Pereira, Oliveira, Tubino, Vila and Balcão.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(i) FTIR spectra of (A) choline bicarbonate, (B) oleic acid, (C) geranic acid, (D) choline oleate 1:1, (E) choline oleate 1:2, (F) choline geranate 1:1, (G) choline geranate 1:2, and (H) human insulin (NOVOLIN^® N); (ii) Thermogravimetric curves (A), 1st derivative of the weight loss curves (B), and differential scanning calorimetry thermograms of plain ionic liquids and their base reactants. The analyses were carried out in a differential scanning microcalorimeter from TA Instruments (model MDSC 2910, New Castle, DE, United States), using high-pressure aluminum pans duly sealed by pressure.