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CMKLR1 gene silencing inhibited the activation of the NLRP3 inflammasome in a rat model of diabetic cardiomyopathy (DCM). (A–E) Relative protein levels of NLRP3, pro-caspase-1, activated caspase-1, and mature IL-1β in the left ventricle of rats in the different groups. Data were presented as means ± SEM from three independent experiments. *p < 0.05, **p < 0.01 vs. Ctrl; § p < 0.05, §§ p < 0.01 vs. DCM+NC. NC, negative control.
