Figure 4. Interval Between Conflicting Interpretations.

An interval was defined as the elapsed time between 2 conflicting interpretations; when multiple conflicting interpretations existed for a single variant, the 2 most recent conflicting interpretations were used. The total number of variants with conflicting interpretations was 84 in the interval of less than 1 year, 76 in the interval of 1 to 2 years, and 41 in the interval of more than 2 years. P/LP indicates pathogenic or likely pathogenic variants; VUS, variants of uncertain significance.