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. 2020 Apr 21;2020:1343969. doi: 10.1155/2020/1343969

Figure 2.

Figure 2

Baicalin alleviated lithogenic diet-induced gallstone and hyperlipidemia in mice. (a) Body weight was recorded and calculated in the mice, which received a lithogenic diet or/and Baicalin treatment. n = 6. (b, c) The representative pictures of the gallbladder of mice with a lithogenic diet or/and Baicalin administration (the arrows indicate the gallbladder). The gallstone positive rate of mice is shown in each group. n = 12. (d) The weight of gallbladders was calculated. (e) HE staining was performed to detect the pathological and physiological characteristics of gallbladder tissues (the scale bar represented 100 μm). (f–j) The content of triglyceride (TG) (f), total cholesterol (TC) (g), high-density lipoprotein cholesterol (HDL-C) (h), low-density lipoprotein cholesterol (LDL-C) (i), and total bile acid (TBA) in serum (j) of mice in each group. (k, l) The content of TC (k) and TBA (l) in bile of mice in each group. n = 6. (m, n) The content of total cholesterol (TC) (m) and triglyceride (TG) (n) in the liver of mice in each group. n = 6 (p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001). ns: no significance; BA(L): 50 mg/kg baicalin; BA(H): 100 mg/kg baicalin.