Table 2.
Clinical characteristics and renal survival of three RA patients with IgA glomerulonephritis following kidney biopsy.
| Case 1 | Case 2 | Case 3 | |
|---|---|---|---|
| METS-C score | M1, E0, S1, T2, C0 | M1, E1, S1, T2, C0 | M1, E1, S1, T2, C0 |
| Therapy after kidney biopsy | |||
| Steroids in months | 24 | 24 | 24 |
| Methotrexate in months | — | — | 24 |
| Original TNF-α inhibitor in months | 24 | 19 | — |
| Rituximab (number of cycles) | 3 | 3 | 4 |
| Endoxan/Azathioprine | No | Yes | No |
| DAS28 one year after biopsy | 3.08 | 2.76 | 4.54 |
|
| |||
| Renal survival after biopsy | 2 years | 1 year | 1 year |
| 24 h urine proteinuria (g/dU) | 2.26 | 3.00 | 0.68 |
| Serum creatinine (μmol/L) | 195 | 103 | 88 |
| eGFR (mL/min/1.73 m2) | 35.3 | 60.2 | 61.1 |
|
| |||
| Renal survival after biopsy | 4 years | 2 years | 2 years |
| 24 h urine proteinuria (g/dU) | 1.57 | 0.09 | 0.13 |
| Serum creatinine (μmol/L) | 166 | 87 | 83 |
| eGFR (mL/min/1.73 m2) | 42.2 | 73.3 | 65.1 |
eGFR-estimated glomerular filtration rate.