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. 2020 Apr 20;2020:8348035. doi: 10.1155/2020/8348035

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Copyright © 2020 Xiuya Yao et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Vanillic acid (VA) pretreatment inhibits apoptosis in H9c2 cells exposed to hypoxia/reoxygenation (H/R), while AMPKα2-siRNA abrogates this effect. (a) H9c2 cells were sectioned and analysed for apoptosis using TUNEL staining. The panels show representative histological images. (b) The number of apoptotic cells evaluated by TUNEL is expressed as a percentage. Data are expressed as the mean ± SEM, n = 3. ^∗∗p < 0.01 vs. control group; ^▲▲p < 0.01 vs. H/R group; ^##p < 0.01 vs. VA+H/R group.