Table 5.
Univariate logistic analysis of factors associated with clinical response to SLIT.
| Characteristic | Group | P value | |
|---|---|---|---|
| Effective | Ineffective | ||
| Number (%) | 303 (65%) | 163 (35%) | 0.010 |
| Age (years) | 7.3 (6.1-9.2) | 7.8 (6.3-9.5) | 0.134 |
| Male (%) | 170 (56.1%) | 96 (58.9%) | 0.204 |
| BMI | 22 (18.7-25.3) | 21.5 (18.1-26.7) | 0.363 |
| Diet habits (%) | |||
| Seafood | 21.5% | 20.3% | 0.181 |
| Poultry | 48.1% | 53.2% | 0.172 |
| Pork | 75.2% | 73.8% | 0.346 |
| Fast food | 12.1% | 11.6% | 0.067 |
| Beverages | 18.5% | 21.3% | 0.112 |
| Outdoor activities | |||
| 0-1 hour | 34% | 41% | 0.231 |
| 1-2 hours | 42% | 41% | 0.135 |
| >3 hours | 24% | 19% | 0.087 |
| Bedroom time | |||
| <12 hours | 90% | 85% | 0.246 |
| >12 hours | 10% | 15% | 0.417 |
| Living environment | |||
| Bungalows/building | 5%/95% | 3%/97% | 0.421 |
| Urban/rural area | 82%/18% | 85%/15% | 0.653 |
| Atopic family history | 57% | 68% | 0.512 |
| Pet raising | 8% | 5% | 0.214 |
| Plush toys (%) | 32% | 29% | 0.128 |
| Parental smoking (%) | 65% | 59% | 0.119 |
| Education background (%) | |||
| <Master's degree | 38% | 48% | 0.013 |
| >Master's degree | 62% | 52% | 0.024 |
| Air conditioning service time | |||
| <3 months/year | 21% | 10% | 0.006 |
| >3 months/year | 79% | 90% | 0.008 |
| Bedding cleaning | |||
| <1 time | 14% | 18% | 0.128 |
| >1 time | 86% | 82% | 0.226 |
| Wall material | |||
| Wallpaper | 11% | 15% | 0.019 |
| Organic solvent coating | 85% | 78% | 0.028 |
| Aqueous coating | 4% | 7% | 0.037 |
| Floor material | |||
| Carpet | 14% | 12% | 0.371 |
| Ceramic tile | 63% | 76% | 0.446 |
| Wood floor | 23% | 12% | 0.257 |
| Cooking fuel | |||
| Coal gas | 54% | 42% | 0.183 |
| Oil gas | 25% | 30% | 0.763 |
| Natural gas | 21% | 28% | 0.683 |
| Duration of disease | |||
| <1 year | 33% | 38% | 0.051 |
| 1-2 years | 21% | 19% | 0.117 |
| >3 years | 46% | 43% | 0.235 |
| Age of onset | 4 (3-6) | 4.5 (3-6) | 0.411 |
| Severity | |||
| Mild | 23% | 25% | 0.371 |
| Moderate | 46% | 48% | 0.426 |
| Severe | 31% | 27% | 0.553 |
| t-IgE | 321.5 (178.5, 534) | 413 (103, 852) | 0.002 |
| IgG4 | 10.4 (8.3, 11.8) | 12.2 (10.9, 14.1) | 0.226 |
| s-IgE of Der f | 27.7 (10.7, 68.8) | 17.9 (7.3, 42.9) | 0.001 |
| s-IgE/t-IgE ratios | 36.1 (21.7, 42.9) | 17.8 (15.6, 21.4) | 0.003 |
| Blood leukocyte count (×109/L) | 5.88 (5.03-7.53) | 6.02 (5.18-7.88) | 0.358 |
| Blood neutrophil count (×109/L) | 3.07 (2.53-3.85) | 3.12 (2.68-4.05) | 0.426 |
| Blood neutrophil percent (%) | 49.1 (45.3-57.6) | 47.8 (48.5-59.2) | 0.189 |
| Blood lymphocyte count (×109/L) | 2.07 (1.69-2.78) | 2.01 (1.71-2.65) | 0.773 |
| Blood lymphocyte percent (%) | 33.1 (29.5-42.8) | 35.9 (28.7-44.6) | 0.653 |
| Blood eosinophil count (×109/L) | 0.21 (0.13-0.48) | 0.19 (0.11-0.38) | 0.129 |
| Blood eosinophil percent (%) | 3.65 (2.34-8.67) | 2.97 (1.78-6.83) | 0.137 |
| Blood monocyte count (×109/L) | 0.42 (0.35-0.56) | 0.43 (0.33-0.59) | 0.133 |
| Blood monocyte percent (%) | 7.64 (6.34-9.81) | 7.42 (6.15-8.95) | 0.245 |
| Blood basophil count (×109/L) | 0.06 (0.03-0.11) | 0.05 (0.04-0.10) | 0.378 |
| Blood basophil percent (%) | 1.03 (0.85-1.04) | 0.98 (0.87-1.08) | 0.198 |
| ECP (ng/mL) | 40.2 (5.6-128.4) | 51.3 (7.8-145.1) | 0.266 |
| IL-4 (pg/mL) | 3.4 (2.1-4.5) | 3.8 (1.9-4.7) | 0.098 |
| IL-5 (pg/mL) | 87.3 (45.8-137.8) | 73.2 (41.6-119.5) | 0.178 |
| IL-13 (pg/mL) | 1256.8 (783.1-1428.3) | 1198.5 (68-1428.3) | 0.264 |
| IL-12 (pg/mL) | 78.2 (52.1-124.6) | 67.1 (41.9-117.8) | 0.073 |
| IFN-γ (pg/mL) | 245.1 (178.3-301.6) | 218.3 (166.4-285.0) | 0.133 |
| IL-17 (pg/mL) | 124.5 (86.9-147.3) | 137.8 (97.8-185.2) | 0.187 |
| IL-10 (pg/mL) | 92.5 (71.3-101.6) | 69.3 (63.1-80.1) | 0.002 |
| IL-35 (pg/mL) | 187.3 (146.5-221.8) | 106.2 (85.3-127.3) | 0.001 |
| TGF-beta (pg/mL) | 192.1 (132.5-223.4) | 187.6 (124.6-211.7) | 0.004 |
Mean (95% CI). bGeometric mean after logarithmic transformation (95% CI).