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Comparison of metal concentrations between control and Mn-supplemented intestine-specific Zip14 knockout (I-KO). Mn concentrations in blood (A) and brain (B) and Zn and Fe concentrations in the brain (C) were measured by Microwave Plasma-Atomic Emission Spectrometer. Values are means ± SD; n = 6 (both female and male mice were included). Significance was assessed by one-way ANOVA. fl/fl, floxed Zip14.
