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Comparison of motor functions between control and Mn-supplemented intestine-specific Zip14 knockout (I-KO) mice. Time to cross the balance beam and fecal output were counted (A). Reactive oxygen species (ROS) (B) and cytokine expressions (C) were measured. Values are means ± SD; n = 6 (both female and male mice were included). Significance was assessed by one-way ANOVA. fl/fl, floxed Zip14; iNOS, inducible nitric oxide synthase.
