Fig. 3.

Local hemodynamic and muscle oxygenation responses to plantar flexion exercise in peripheral artery disease (PAD) patients and healthy controls. Data are expressed as means ± SE. Data are collected from the leg of patients with PAD (n = 10, ●) and same leg of the matched healthy controls (n = 10, ○). Data are from exercising leg (most symptomatic leg) on visit 1. MAP, mean arterial pressure; FBF, femoral blood flow; $\text{S}{\text{m}}_{{\text{O}}_2}$, skeletal muscle oxygen saturation. *P < 0.05, significant difference between control and PAD. ^P < 0.05, significant difference from baseline in patients with PAD. +P < 0.05, significant difference from baseline in healthy control.