Table 4.
P1S1, mL/min | P2S2, mL/min | Kpgp, mL/min | k̄2, mL/min | k−2, min−1 | Kd3 | Δψm, mV | |
---|---|---|---|---|---|---|---|
R6G | 48.04 ± 7.05 | 0.683 ± 0.154 | 10.80 ± 5.38 | 13.93 ± 2.56 | 0.121 ± 0.013 | 0.031 ± 0.009 | −144.26 ± 23.93 |
R6G + verapamil | 49.69 ± 8.78 | 1.123 ± 0.291 | 0 | 7.30 ± 0.73 | 0.170 ± 0.019 | 0.016 ± 0.004 | −130.70 ± 14.67 |
Values are mean ± SD estimated values of model parameters (Monte Carlo approach): 100 different fits to the mean data in the absence or presence of verapamil with the initial values of model parameters equal to the mean values of the fits to individual experiments (Table 3) ± a uniformly distributed random value within ±30% of this mean error. R6G, rhodamine 6G.