Table 2.
Hemodynamic, brachial artery and metabolic parameters before acute treadmill exercise, and at 30, 60, and 120 min after treadmill exercise, during placebo, resveratrol, and estradiol treatments
Placebo |
Resveratrol |
Estradiol |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Preexercise | 30 min | 60 min | 120 min | Preexercise | 30 min | 60 min | 120 min | Preexercise | 30 min | 60 min | 120 min | |
FMD | ||||||||||||
Brachial diameter, mm | 3.85 ± 0.12 | 3.90 ± 0.11 | 3.87 ± 0.11 | 3.79 ± 0.11 | 3.69 ± 0.10 | 3.71 ± 0.10 | 3.74 ± 0.10 | 3.67 ± 0.10 | 3.68 ± 0.11 | 3.73 ± 0.11 | 3.77 ± 0.11 | 3.74 ± 0.11 |
Brachial FMD, mm∆ | 0.16 ± 0.02 | 0.14 ± 0.02 | 0.13 ± 0.02 | 0.16 ± 0.02 | 0.25 ± 0.03* | 0.22 ± 0.03* | 0.26 ± 0.03* | 0.27 ± 0.03* | 0.22 ± 0.02* | 0.21 ± 0.03* | 0.27 ± 0.03*† | 0.31 ± 0.02*† |
Blood markers | ||||||||||||
Glucose, mg/dL | 93 ± 2 | 93 ± 2 | 92 ± 2 | 94 ± 2 | 94 ± 2 | 92 ± 2 | 90 ± 2*§ | 91 ± 2§ | 90 ± 2 | |||
Insulin, mIU/L | 6.8 ± 0.8 | 6.6 ± 0.8 | 6.2 ± 0.8 | 6.4 ± 1.0 | 6.1 ± 1.0 | 6.3 ± 1.0 | 5.9 ± 0.7 | 5.9 ± 0.7 | 5.6 ± 0.7 | |||
Estradiol, pg/mL | 10.6 ± 3.2 | 10.5 ± 3.6 | 64.6 ± 26.6*§ | |||||||||
HR and BP FMD | ||||||||||||
HR, bpm | 58 ± 1 | 68 ± 1† | 64±1† | 59 ± 1 | 59±1 | 57 ± 2† | 66 ± 2† | 58 ± 2 | 58 ± 1 | 68 ± 1† | 64 ± 1† | 60 ± 1† |
SBP, mmHg | 114 ± 2 | 108 ± 2† | 110±2† | 113 ± 2 | 115±2 | 107 ± 2† | 108 ± 2† | 115 ± 2 | 109 ± 1*§ | 104 ± 1† | 104 ± 1†* | 108 ± 1*§ |
DBP, mmHg | 69 ± 2 | 66 ± 2† | 67±2† | 69 ± 2 | 71±2 | 66 ± 2† | 66 ± 2† | 70 ± 2 | 66 ± 2§ | 63 ± 2† | 64 ± 2* | 67 ± 2* |
MAP, mmHg | 84 ± 2 | 81 ± 2† | 82±2 | 85 ± 2 | 88±2 | 81 ± 2† | 82 ± 2† | 86 ± 2 | 81 ± 1§ | 77 ± 1†§ | 78 ± 1†§ | 82 ± 1§ |
Values presented for the 15 subjects are expressed as means ± SE. BP, blood pressure; bpm, beats per minute; HR, heart rate; MAP, mean arterial pressure.
Significantly different (P < 0.05) from placebo condition at same time point.
Significantly different (P < 0.05) from pre-exercise within condition.
Significantly different (P < 0.05) from resveratrol at the same time point.