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. 2020 Mar 5;128(4):739–747. doi: 10.1152/japplphysiol.00488.2019

Table 2.

Hemodynamic, brachial artery and metabolic parameters before acute treadmill exercise, and at 30, 60, and 120 min after treadmill exercise, during placebo, resveratrol, and estradiol treatments

Placebo
Resveratrol
Estradiol
Preexercise 30 min 60 min 120 min Preexercise 30 min 60 min 120 min Preexercise 30 min 60 min 120 min
FMD
    Brachial diameter, mm 3.85 ± 0.12 3.90 ± 0.11 3.87 ± 0.11 3.79 ± 0.11 3.69 ± 0.10 3.71 ± 0.10 3.74 ± 0.10 3.67 ± 0.10 3.68 ± 0.11 3.73 ± 0.11 3.77 ± 0.11 3.74 ± 0.11
    Brachial FMD, mm∆ 0.16 ± 0.02 0.14 ± 0.02 0.13 ± 0.02 0.16 ± 0.02 0.25 ± 0.03* 0.22 ± 0.03* 0.26 ± 0.03* 0.27 ± 0.03* 0.22 ± 0.02* 0.21 ± 0.03* 0.27 ± 0.03* 0.31 ± 0.02*
Blood markers
    Glucose, mg/dL 93 ± 2 93 ± 2 92 ± 2 94 ± 2 94 ± 2 92 ± 2 90 ± 2*§ 91 ± 2§ 90 ± 2
    Insulin, mIU/L 6.8 ± 0.8 6.6 ± 0.8 6.2 ± 0.8 6.4 ± 1.0 6.1 ± 1.0 6.3 ± 1.0 5.9 ± 0.7 5.9 ± 0.7 5.6 ± 0.7
    Estradiol, pg/mL 10.6 ± 3.2 10.5 ± 3.6 64.6 ± 26.6*§
HR and BP FMD
    HR, bpm 58 ± 1 68 ± 1 64±1 59 ± 1 59±1 57 ± 2 66 ± 2 58 ± 2 58 ± 1 68 ± 1 64 ± 1 60 ± 1
    SBP, mmHg 114 ± 2 108 ± 2 110±2 113 ± 2 115±2 107 ± 2 108 ± 2 115 ± 2 109 ± 1*§ 104 ± 1 104 ± 1* 108 ± 1*§
    DBP, mmHg 69 ± 2 66 ± 2 67±2 69 ± 2 71±2 66 ± 2 66 ± 2 70 ± 2 66 ± 2§ 63 ± 2 64 ± 2* 67 ± 2*
    MAP, mmHg 84 ± 2 81 ± 2 82±2 85 ± 2 88±2 81 ± 2 82 ± 2 86 ± 2 81 ± 1§ 77 ± 1§ 78 ± 1§ 82 ± 1§

Values presented for the 15 subjects are expressed as means ± SE. BP, blood pressure; bpm, beats per minute; HR, heart rate; MAP, mean arterial pressure.

*

Significantly different (P < 0.05) from placebo condition at same time point.

Significantly different (P < 0.05) from pre-exercise within condition.

§

Significantly different (P < 0.05) from resveratrol at the same time point.