Table 3.

Clinical sleep parameters for all subjects on placebo and acetazolamide

	Placebo	Acetazolamide
Sleep efficiency, %	83.5 ± 10.6	79.1 ± 12.2
PLMAI (events/h)	0.3 ± 0.5	1.1 ± 1.7*
RERAI (events/h)	23.9 ± 21.8	21.0 ± 17.3
AHI (events/h)	39.3 ± 24.1	28.8 ± 22.9*
CAI (events/h)	6.3 ± 13.1	0.6 ± 1.5*
ODI (events/h)	19.2 ± 15.2	7.5 ± 8.3*

AHI, apnea-hypopnea index; CAI, central apnea index; ODI, oxyhemoglobin desaturation index PLMAI, periodic leg movement arousal index; RERAI, respiratory effort-related arousal index.

^*P < 0.05 vs. placebo using one-tailed, paired-samples t test.