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. Author manuscript; available in PMC: 2020 Apr 30.
Published in final edited form as: Clin Sci (Lond). 2019 Nov 29;133(22):2329–2344. doi: 10.1042/CS20190578

Figure 1. Adipose-mediated paracrine signaling effects on the heart.

Figure 1.

WAT (yellow color), comprising PVAT, EAT, visceral, subcutaneous, and gonadal, is composed of droplet-rich and mitochondrial poor white adipocytes. BAT (brown color), comprising cervical, supraclavicular, auxillary, paravertebral, and suprarenal, is composed of multilocular and mitochondrial rich brown adipocytes. WAT releases several adipokines, which can result in cardioprotection, but is often associated with increased CVD, including hypertrophied cardiomyocytes and collagen deposition (blue). BAT releases BATokines that are most often associated with promoting healthy myocardium and cardioprotection from ischemic injury.