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. 2020 Apr 27;6(4):e03844. doi: 10.1016/j.heliyon.2020.e03844

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© 2020 Published by Elsevier Ltd.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

(a) The effect of progesterone administration at 2 h after TBI on serum ratio of NGF/IL-6 in OVX rats (n = 7). ^##P < 0.01, vs. Veh. (b) The effect of capsule form of progesterone on serum ratio of NGF/IL-6 in OVX rats (n = 7). ⁺⁺⁺P < 0.001, vs. Cveh. (c) Changes in percentage of serum ratio of NGF/IL-6 after TBI compared with vehicle in rats treated with progesterone (n = 7). ^& P < 0.05, vs. LP. Sh, sham; Veh, vehicle; LP, low progesterone; HP, high progesterone; CP, progesterone capsule; Cveh, capsule vehicle.