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Median parameter values for compounds with lower vs. higher CV values with (n)
| CV | fub | fup | # Rot Bonds | HBA & HBD | LogD | CLint, in vivo | LogP | PSA | HBA | VDSS | CLint, in vivo | MRT | fuhep | MW | # Aromatic Rings | HBD |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| <50% | 0.067(17) | 0.053(17) | 4.0(17) | 6.0(17) | 2.2(17) | 5.4(17) | 2.5(17) | 57(17) | 4.0(17) | 1.2(17) | 96(17) | 3.3 (17) | 0.88(17) | 314(17) | 2.0(17) | 1.0(17) |
| >50% | 0.16(16) | 0.1 1 (16) | 2.5(16) | 4.5(16) | 1.7(16) | 6.8(16) | 2.9(16) | 50(16) | 3.5(16) | l.l (15) | 103(16) | 3.5(15) | 0.91 (16) | 304(16) | 2.0(16) | 1.0(16) |
