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. Author manuscript; available in PMC: 2020 May 31.
Published in final edited form as: Pharm Res. 2019 May 31;36(8):113. doi: 10.1007/s11095-019-2645-0

Table IV.

Properties of Compounds with Accurate, Uniform Predictions

Parameter #Accurate #Inaccurate %Accurate
LogD
<1.0 5 7 41.7%
≥1.0 18 5.26%
CLint, in vivo
<100 5 31.3%
≥100 14 6.67%
fup
<0.1 2 17 10.5%
≥0.1 4 8 33.3%