Table 2 Baseline characteristics according to mvPA
| mvPA > 9 cm/s n = 115 |
mvPA ≤9 cm/s n = 95 |
Total n = 210 |
p value | |
|---|---|---|---|---|
| Echocardiography | ||||
| LVEF (%) | 28.9 ± 9.8 | 26.4 ± 9.0 | 27.8 ± 9.6 | 0.056 |
| LVEDD (mm) | 58.7 ± 7.7 | 60.1 ± 7.2 | 59.3 ± 7.5 | 0.288 |
| LVESD (mm) | 46.8 ± 9.2 | 48.7 ± 8.9 | 47.6 ± 9.1 | 0.238 |
| RV diameter (mm) | 22.3 ± 5.3 | 25.4 ± 7.8 | 23.9 ± 6.9 | 0.010 |
| TAPSE (mm) | 17.8 ± 5.1 | 16.0 ± 4.2 | 48.1 ± 14.5 | 0.044 |
| SPAP (mmHg)a | 46.8 ± 16.2 | 49.4 ± 12.7 | 16.9 ± 4.7 | 0.321 |
| TAPSE/sPAP ratio (mm/mmHg)a | 0.45 ± 0.27 | 0.34 ± 0.15 | 0.39 ± 0.22 | 0.020 |
| CMR | ||||
| LVEF (%) | 28.8 ± 10.4 | 24.4 ± 9.0 | 26.9 ± 10.0 | 0.001 |
| LVEDVI (mL/m2) | 124.3 ± 41.0 | 136.2 ± 45.2 | 129.7 ± 43.2 | 0.047 |
| LVESVI (mL/m2) | 91.1 ± 40.2 | 103.5 ± 43.0 | 96.7 ± 41.8 | 0.033 |
| RVEF (%) | 46.1 ± 14.6 | 39.4 ± 16.2 | 43.1 ± 15.7 | 0.002 |
| RVEDVI (mL/m2) | 71.2 ± 27.8 | 84.1 ± 36.2 | 77.1 ± 32.5 | 0.004 |
| RVESVI (mL/m2) | 39.3 ± 21.4 | 53.9 ± 32.5 | 45.9 ± 27.9 | < 0.001 |
| LGE ischemic-pattern(n,%) | 28(29.8%) | 27(36%) | 55(32.5%) | 0.392 |
| LGE non-ischemic pattern(n,%) | 33(35.5%) | 35(47.3%) | 68(40.7%) | 0.123 |
| mvPA (cm/s) | 12.7 ± 3.4 | 7.0 ± 1.6 | 10.1 ± 3.9 | < 0.001 |
| PVR (WU) | 3.9 ± 1.7 | 7.3 ± 1.8 | 5.5 ± 2.4 | < 0.001 |
| RV-PA unit parameters | ||||
| Maximal PA-area (cm2) | 7.9 ± 2.0 | 9.3 ± 2.5 | 8.6 ± 2.4 | < 0.001 |
| Minimal PA-are a (cm2) | 5.9 ± 1.8 | 7.3 ± 1.8 | 6.6 ± 2.1 | < 0.001 |
| PA pulsatility(%) | 0.35 ± 0.19 | 0.30 ± 0.15 | 0.33 ± 0.18 | 0.068 |
| RV Emax/Ea | 1.03 ± 0.66 | 0.76 ± 0.52 | 0.91 ± 0.61 | 0.002 |
| Right heart catheterisation parameters | ||||
|
mvPA > 9 cm/s n = 27 |
mvPA ≤ 9 cm/s n = 28 |
Total n = 55 |
p value | |
| mPAP (mmHg) | 29.4 ± 11.7 | 33.4 ± 8.9 | 31.4 ± 10.5 | 0.162 |
| PCWP (mmHg) | 20.6 ± 8.2 | 21.1 ± 7.7 | 20.8 ± 7.8 | 0.808 |
| RA Pressure (mmHg) | 11.1 ± 6.9 | 13.4 ± 5.9 | 12.3 ± 6.4 | 0.243 |
| Cardiac output (l/min) | 4.1 ± 1.6 | 3.2 ± 1.1 | 3.6 ± 1.4 | 0.063 |
| PVR (WU) | 2.8 ± 2.4 | 4.1 ± 2.3 | 3.4 ± 2.4 | 0.096 |
| TPG (mmHg) | 8.5 ± 6.9 | 12.6 ± 7.4 | 10.6 ± 7.4 | 0.042 |
| Pulse Pressure (mmHg) | 21.0 ± 9.5 | 29.6 ± 13.2 | 25.4 ± 12.9 | 0.012 |
| PA Compliance (mm3/mmHg) | 2.02 ± 0.94 | 1.39 ± 0.79 | 1.67 ± 0.90 | 0.022 |
a Measures available for 139 patients
CMR cardiovascular magnetic resonance. Ea effective elastance. Emax right ventricular maximal end-systolic elastance. LVEDVI left ventricular end-diastolic volume index. LVESV left ventricular end-systolic volume index. RVEDV right ventricular end-diastolic volume index. RVESV right ventricular end-systolic volume index. LGE late gadolinium enhancement. LVEF left ventricular ejection fraction. LVEDD left ventricular end-diastolic diameter. LVESD left ventricular end-systolic diameter. MPAP mean pulmonary artery pressure. mvPA mean velocity at the pulmonary artery. PA pulmonary artery. PCWP pulmonary capillary wedge pressure. PVR pulmonary vascular resistance. RA right atrium. RV right ventricle. RVEF right ventricular ejection fraction. sPAP systolic pulmonary artery pressure. TAPSE tricuspid annular plane excursion. TPG transpulmonary gradient. WU wood units