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. 2020 Apr 29;12:36. doi: 10.1186/s13098-020-00544-0

Table 5.

Unadjusted and adjusted correlation of MALAT1 gene expression in SAT and VAT of the whole population study with energy homeostasis-related genes

Characteristics lncRNA MALAT1 in SAT lncRNA MALAT1 in VAT
Whole Population Whole Population
Unadjusted Pearson coefficient Adjusted for age and HOMA-IR Pearson coefficient Unadjusted Pearson coefficient Adjusted for age and HOMA-IR Pearson coefficient
PPARγ 0.329a 0.299 0.070 0.086
PGC1α 0.153 0.250 0.455b 0.424b
SREBP 0.640b 0.589b 0.225 0.193
FAS 0.573b 0.513b 0.261 0.210
ACC 0.411b 0.401b 0.186 0.153
LncRNA TUG1 0.299 0.346a − 0.380a − 0.324a

SAT, subcutaneous adipose tissue; VAT, visceral adipose tissue; MALAT1, metastasis-associated lung adenocarcinoma transcript 1; TUG1, taurine upregulated gene 1; PPARγ, peroxisome proliferator-activated receptor gamma; PGC1α, PPARγ coactivator-1 alpha; SREBP-1, sterol regulatory element-binding protein α; FAS, fatty acid synthase; ACC, acetyl-CoA carboxylase; HOMA-IR, homeostasis model assessment of insulin resistance

a Correlation is significant at the 0.05 level (2-tailed)

b Correlation is significant at the 0.01 level (2-tailed)