Table 3.

The incidence of MNPCEs and PCE/NCE ratio in bone marrow of male (♂) and female (♀) Swiss albinus mice after testing for 24 h and 48 h. Data are from the controls (NaCl and NEU) and an evaluation of the genotoxicity of the lyophilized hydroalcoholic extract of S. praealtum leaves

Treatment	MNPCEs (n)		MNPCEs (%)		PCE / (PCE + NCE)
	24 h A	48 h A	24 h A	48 h A	24 h A	48 h A
150 mM NaCl
♀ A (MNPCE); A (PCE/NCE ratio)	8 ± 3	7 ± 3	0.39 ± 0.09	0.33 ± 0.16	1.00 ± 0.00	1.00 ± 0.00
♂ B (MNPCE); B (PCE/NCE ratio)	8 ± 3	11 ± 1	0.37 ± 0.16	0.53 ± 0.06	1.00 ± 0.00	1.00 ± 0.00
Mean ± SD	8 ± 3 A	9 ± 3 A	0.38 ± 0.12 A	0.43 ± 0.15 A	1.00 ± 0.00 A	1.00 ± 0.00 A
N–Nitroso–N–ethylurea (NEU: 50 mg/kg)
♀ A (MNPCE); A (PCE/NCE ratio)	27 ± 9	33 ± 3	1.33 ± 0.43	1.63 ± 0.11	0.54 ± 0.04	0.75 ± 0.12
♂ B (MNPCE); B (PCE/NCE ratio)	68 ± 32	35 ± 5	3.33 ± 1.54	1.74 ± 0.27	0.55 ± 0.10	0.54 ± 0.11
Mean ± SD	48 ± 31 B	34 ± 4 B	2.33 ± 1.50 B	1.69 ± 0.20 B	0.54 ± 0.07 C	0.65 ± 0.16 C
Sedum praealtum A.DC. (500 mg/kg)
♀ A (MNPCE); A (PCE/NCE ratio)	9 ± 7	13 ± 8	0.44 ± 0.34	0.60 ± 0.37	0.90 ± 0.04	0.92 ± 0.02
♂ B (MNPCE); B (PCE/NCE ratio)	4 ± 2	5 ± 1	0.21 ± 0.10	0.24 ± 0.03	0.91 ± 0.03	0.87 ± 0.03
Mean ± SD	7 ± 5 A	9 ± 7 A	0.33 ± 0.26 A	0.42 ± 0.31 A	0.90 ± 0.03 B	0.89 ± 0.03 B
Sedum praealtum A.DC. (1000 mg/kg)
♀ A (MNPCE); A (PCE/NCE ratio)	6 ± 1	18 ± 8	0.31 ± 0.07	0.88 ± 0.38	0.91 ± 0.02	0.91 ± 0.01
♂ B (MNPCE); B (PCE/NCE ratio)	6 ± 1	13 ± 1	0.29 ± 0.07	0.63 ± 0.05	0.91 ± 0.02	0.91 ± 0.02
Mean ± SD	6 ± 1 A	15 ± 6 A	0.30 ± 0.07 A	0.76 ± 0.29 A	0.91 ± 0.02 B	0.91 ± 0.01 B
Sedum praealtum A.DC. (2000 mg/kg)
♀ A (MNPCE); A (PCE/NCE ratio)	9 ± 4	9 ± 2	0.46 ± 0.18	0.44 ± 0.09	0.92 ± 0.01	0.91 ± 0.02
♂ B (MNPCE); B (PCE/NCE ratio)	5 ± 4	25 ± 14	0.22 ± 0.18	1.24 ± 0.66	0.90 ± 0.04	0.91 ± 0.04
Mean ± SD	7 ± 4 A	17 ± 13 A	0.34 ± 0.21 A	0.84 ± 0.61 A	0.91 ± 0.03 B	0.91 ± 0.03 B

Means with the same letter (A, B or C) are not significantly different (p < 0.05)