Table 2. Synthesis of 3-Substituted Quinazoline-2,4-diones 6a–p^a.

^aAll reactions were conducted using 2a–p (1 mmol, 1.0 equiv), (Boc)₂O (1.5 mmol, 1.5 equiv), DMAP (0.1 mmol, 0.1 equiv), isolated yield.

^bThe reaction was run in 3 mL of CH₃CN under the MW condition for 30 min.

^cThe reaction was run in 10 mL of CH₃CN at room temperature for 12 h.