Table 1.
Patient characteristics and associations with the presence of BE on first upper endoscopy
| All subjects (n = 2931) | BE (n = 57) | Non-BE (n = 2874) | Odds ratioa (95% CI) | P | |
|---|---|---|---|---|---|
| Age—mean (SD) | 62.15 (7.2) | 61.86 (6.7) | 62.15 (7.2) | 0.99 (0.96–1.03) | 0.76 |
| Male sex—no. (%) | 1310 (44.7%) | 32 (56.1%) | 1278 (44.5%) | 1.60 (0.94–2.71) | 0.08 |
| Race—no. (%) | 0.26 | ||||
| Non-white | 515 (17.6%) | 6 (10.5%) | 509 (17.7%) | 1.00 (reference) | |
| White | 1557 (53.1%) | 36 (63.2%) | 1521 (52.9%) | 2.01 (0.84–4.79) | |
| Unknown | 859 (29.3%) | 15 (26.3%) | 844 (29.4%) | 1.50 (0.58–3.91) | |
| Ethnicity—no. (%) | 0.94 | ||||
| Hispanic | 511 (17.4%) | 10 (17.5%) | 501 (17.4%) | 1.00 (reference) | |
| Non-hispanic | 1442 (49.2%) | 27 (47.4%) | 1415 (49.2%) | 0.96 (0.46–1.99) | |
| Unknown | 978 (33.4%) | 20 (35.1%) | 958 (33.3%) | 1.04 (0.49–2.25) | |
| BMI—mean (SD) | 28.78 (7.5) | 30.94 (9.6) | 28.74 (7.5) | 1.03 (1.00–1.07) | 0.04 |
| Smoking history—no. (%) | 0.02 | ||||
| Never | 1639 (55.9%) | 23 (40.4%) | 1616 (56.2%) | 1.00 (reference) | |
| Ever | 1067 (36.4%) | 31 (54.4%) | 1036 (36.1%) | 2.10 (1.22–3.63) | |
| Unknown | 225 (7.7%) | 3 (5.3%) | 222 (7.7%) | 0.95 (0.28–3.19) | |
| GERD diagnosis—no. (%) | 694 (23.7%) | 24 (42.1%) | 670 (23.3%) | 2.39 (1.40–4.08) | 0.002 |
| GERD symptom—no. (%) | 156 (5.3%) | 3 (5.3%) | 153 (5.3%) | 0.99 (0.31–3.20) | 1.00 |
| PPI use—no. (%) | 683 (23.3%) | 22 (38.6%) | 661 (23.0%) | 2.10 (1.23–3.61) | 0.01 |
| H2RA use—no. (%) | 197 (6.7%) | 6 (10.5%) | 191 (6.7%) | 1.65 (0.70–3.90) | 0.28 |
| Family history—no. (%) | 67 (2.3%) | 2 (3.5%) | 65 (2.3%) | 1.57 (0.38–6.58) | 0.38 |
BE Barrett’s esophagus, BMI body mass index, CI confidence interval, GERD gastroesophageal reflux disease, H2RA H2-receptor antagonist, PPI proton-pump inhibitor
a
Unadjusted odds ratios for association with BE