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Phylogenetic analysis was carried out using the PhyML programme. The bootstrap consensus tree (100 replicates) was obtained using all four classes of CAs identified in the genome of different bacteria. The two human α-CA isoforms hCA I and II were included in the phylogenetic analysis, too. Legend: α-cluster (pink), β-cluster (yellow), γ-cluster (light blue), and ι-cluster (dark blue).
