Table 3.
Demographics and clinical characteristics by degree of cognitive impairment
| Characteristics | Total Cohort (n=150) | Normal (n=32; 21%) | Mild (n=25; 17%) | Moderate (n=49; 33%) | Severe (n=44; 29%) | Trend P Value |
|---|---|---|---|---|---|---|
| Age, yr | 64±14 | 64±16 | 65±15 | 63±14 | 64±13 | 0.7 |
| Female | 39% | 50% | 32% | 43% | 32% | 0.2 |
| Black | 39% | 34% | 40% | 37% | 44% | 0.5 |
| Education | ||||||
| <12th Grade | 6% | 0% | 8% | 2% | 14% | 0.09 |
| High-school graduate | 42% | 44% | 32% | 49% | 39% | |
| >2 Yr college | 52% | 56% | 60% | 49%) | 48% | |
| Pre-SBP monthly average, mm Hg | 138±19 | 135±20 | 136±18 | 141±21 | 139±18 | 0.4 |
| Pre-DBP monthly average, mm Hg | 73±11 | 72±12 | 73±11 | 74±11 | 74±10 | 0.7 |
| Stroke | 17% | 16% | 12% | 20% | 16% | 0.8 |
| Peripheral vascular disease | 7% | 13% | 12% | 0% | 9% | 0.3 |
| Diabetes | 51% | 41% | 56% | 51% | 55% | 0.3 |
| Heart failure | 25% | 25% | 24% | 33% | 18% | 0.7 |
| Coronary artery disease | 18% | 19% | 8% | 29% | 11% | 0.9 |
| Primary cause of ESKD | ||||||
| Diabetes | 37% | 21% | 40% | 43% | 41% | |
| Hypertension | 26% | 28% | 28% | 22% | 27% | 0.3 |
| GN or other | 37% | 52% | 32% | 35% | 32% | |
| Dialysis vintage, yr | 2.7 (1.3, 5.6) | 3.6 (1.6, 7.2) | 2.1 (1.2, 5.0) | 2.5 (0.9, 4.9) | 2.3 (1.5, 5.6) | 0.6 |
| Vascular access | ||||||
| Fistula | 83% | 84% | 88% | 84% | 77% | |
| Graft | 9% | 6% | 8% | 8% | 11% | 0.6 |
| Catheter | 9% | 9% | 4% | 8% | 11% | |
| Body mass index, kg/m2 | 28±7 | 28±7 | 29±10 | 28±5 | 27±6 | 0.7 |
| Single-pool Kt/V | 1.51±0.25 | 1.63±0.34 | 1.45±0.16 | 1.49±0.24 | 1.50±0.22 | 0.2 |
| Albumin, g/dl | 4.0±0.4 | 4.0±0.3 | 4.1±0.2 | 4.0±0.5 | 3.9±0.4 | 0.1 |
| CES-D | 14.0±9.3 | 16.0±10.3 | 10.8±7.4 | 14.6±8.8 | 13.4±9.9 | 0.5 |
| Use of nondominant hand for tests | 6% | 4% | 6% | 5% | 5% | 0.5 |
Data are presented either as n (%), mean±SD, or median (25th, 75th percentiles). SBP, systolic BP; DBP, diastolic BP; CES-D, Center for Epidemiologic Studies Depression Scale.