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. 2020 Apr 18;26:e922782-1–e922782-13. doi: 10.12659/MSM.922782

Figure 6.

Figure 6

let-7d-5p directly inhibited the expression of TGF-βRI. (A) The expression of TGF-βRI under different treatments was tested by Western blotting. (B) The expression of TGF-βRI mRNA under different treatments was tested by qRT-PCR. (C) Schematic representation of matching sequence between TGF-βRI 3′UTR mRNA and let-7d-5p. (D) Luciferase activity of ATII cells co-transfected with reporter plasmid (“TGF-βRI wt” or “TGF-βRI mt”) and let-7d-5p or miRNA-NC. (* p<0.05; ** p<0.01; *** p<0.001).