Table 1.

The IC₅₀ values (in μM) of potent organorhenium complexes on breast cancer cells

Compound IC50		MCF-7A error (±)	MCF-10A IC50	Error (±)	Compound IC50		MDA-MB-231 error (±)
TOS7	0.337	0.303	1.78	0.173	TOS7	0.248	0.336
PIC4	0.425	0.226	0.023	0.002	NIC7	0.591	0.145
1NS7	0.849	0.255	2.51	0.187	1NS7	0.716	0.242
IB6	0.958	0.261	1.47	0.177	PIC7	1.03	0.181
1B4	1.25	0.607	12.1	0.554	IB6	1.06	0.375
TOS6	1.27	0.228	3.46	0.186	2NS6	1.08	0.198
2NS6	1.31	0.297	2.79	0.250	PIC6	1.23	0.197
NIC7	1.33	0.29	6.38	0.316	TOS6	1.27	0.361
PIC6	1.51	0.243	3.02	0.133	1NS6	1.53	0.143
1NS4	1.54	0.179	1.59	0.351	FN4	1.7	0.314
TOS4	1.55	0.285	5.7	0.337	TP7	1.74	0.140
FN4	1.56	0.420	2.65	0.253	2NS4	1.86	0.318
2NS4	1.58	0.263	1.66	0.229	TP6	1.99	0.341
PIC7	1.65	0.171	6.31	0.240	ASP7	2.41	0.328
1NS6	1.7	0.226	3.63	0.403	TP4	2.59	0.472
FNS	1.89	0.313	11.1	1.88	1NS4	2.78	0.373
2NS5	2.11	0.267	6.32	0.157	NIC4	2.97	0.172
IB5	2.55	0.673	3.37	0.406	ASP4	3.01	0.252
MF4	2.61	0.496	NA		TOS4	3.09	0.284
1B2	2.69	0.334	12.1	0.298	FN6	3.27	0.212
FN6	2.75	0.315	3.68	0.299	TOSS	3.55	0.537
FN5	2.8	0.267	6.09	0.397	NIC8	3.58	0.331
2N58	2.83	0.516	1.51	0.201	NIC3	3.64	0.625
NIC4	2.93	0.363	5.83	0.264	NIC6	4.24	0.212
MF2	2.95	0.314	12.1	0.287	2N58	5.4	1.02
NIC8	2.98	0.535	5.62	0.248	ASPS	5.76	0.271
TP7	2.98	0.292	3.04	0.431	ASP9	6.02	0.289
1N52	3.09	0.528	11.6	0.872	2N55	6.04	0.204
ASP9	3.11	0.403	6.48	0.318	TF6	6.08	0.357
TP8	3.11	0.376	12.3	0.368	1NS3	6.11	0.601
TOSS	3.12	0.399	6.08	0.143	IB4	6.17	0.767
IB3	3.16	0.406	12.1	0.263	PIC8	6.18	0.164
TOS2	3.24	0.557	6.75	0.444	FN3	6.33	0.494
NIC8	3.25	0.482	6.08	0.160	2N57	6.34	0.486
MF1	3.27	0.473	12.9	0.514	TP5	6.39	0.505
1NS3	3.29	0.517	6.08	0.357	PIC4	6.39	0.362
NIC1	3.37	0.992	>24		ASPS	6.41	0.261
PIC8	3.39	0.353	6.36	0.135	TF8	6.44	0.388
PIC2	3.51	0.410	11.7	0.347	IBS	6.47	0.736
ASP2	3.54	0.487	12.2	0.237	NP6	6.48	0.577
NIC6	3.57	0.988	7.16	1.29	NIC8	6.48	0.187
TOS8	3.61	0.418	6.27	0.186	NP7	6.52	0.384
TF8	3.7	0.383	12.1	0.453	PIC8	6.53	0.467
MF3	4.17	1.45	12	0.374	TOS8	6.54	0.269

NA: not active