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. 2020 Apr 22;11:311. doi: 10.3389/fgene.2020.00311

TABLE 3.

Univariable and multivariable Cox regression analysis of patient clinical characteristics.

Variable Univariate analysis
Multivariate analysis
HR 95%CI P-value HR 95%CI P-value
Age 1.010 0.991–1.030 0.296
Sex (female/male) 0.670 0.633–1.342 0.921
Race (Caucasian/non-Caucasian) 2.330 1.246–4.355 0.008 2.327 1.222–4.429 0.016
Smoke history (no/yes) 0.671 0.337–1.335 0.256
T stage (T1-T2/T3-T4) 1.449 1.134–1.851 0.003 1.241 1.032–1.492 0.021
N stage (N1-N2/N3-N4) 1.709 1.367–2.136 <0.001 2.800 1.796–4.366 <0.001
M stage (M0/M1) 1.654 0.804–3.403 0.172
Chemotherapy (No/Yes) 0.780 0.065–0.098 0.041 0.634 0.410–0.980 0.040
Radiotherapy (No/Yes) 2.025 1.310–3.130 0.001 1.369 0.828–2.265 0.221
Risk score (Low/High) 2.707 1.782–4.112 <0.001 2.533 1.645–3.901 <0.001