REAGENT or RESOURCE	SOURCE	IDENTIFIER
Biological Samples
Oropharyngeal swab samples from COVID-19 cases	This study	N.A.
Whole blood derived RNA samples from COVID-19 cases	This study	N.A.
Critical Commercial Assays
bioMerieux NucliSENS easyMAG	bioMerieux	N.A.
SuperScript III Platinum One-Step Quantitative RT-PCR system	Invitrogen	Cat# 11732-088
Tempus™ Blood RNA Tube	Applied Biosystems	Cat# 4342792
Tempus™ Spin RNA Isolation Kit	Invitrogen	Cat# 4380204
nCounter® Human Immunology v2 Panel	NanoString Inc.	Cat# XT-CSO-HIM2-12
Oligonucleotides
E_Sarbeco_F: 5′-ACAGGTACGTTAATAGTTAATAGCGT-3′	Corman et al., 2020; IDT	N.A.
E_Sarbeco_R: 5′-ATATTGCAGCAGTACGCACACA-3′	Corman et al., 2020; IDT	N.A.
E_Sarbeco_P1: 5′-FAM-ACACTAGCCATCCTTACTGCGCTTCG-BHQ1-3′	Corman et al., 2020; IDT	N.A.
RdRp_SARSr-F: 5′-GTGARATGGTCATGTGTGGCGG-3′	Corman et al., 2020; IDT	N.A.
RdRp_SARSr-R: 5′-CARATGTTAAASACACTATTAGCATA-3′	Corman et al., 2020; IDT	N.A.
RdRP_SARSr-P1: 5′-FAM-CCAGGTGGWACRTCATCMGGTGATGC-BHQ1-3′	Corman et al., 2020; IDT	N.A.
RdRp_SARSr-P2: 5′-FAM-CAGGTGGAACCTCATCAGGAGATGC-BHQ1-3′	Corman et al., 2020; IDT	N.A.
Deposited Data
Raw and analyzed data for NanoString profiling of healthy controls and COVID-19 cases	This paper	ArrayExpress: E-MTAB-8871
Software and Algorithms
Philips Vue Picture Archiving and Communication System (PACS) version 12.2	Philips	N.A.
Philips Vue Reporting Information System (RIS) version 11.2	Philips	N.A.
GraphPad Prism version 8.3	GraphPad Software	N.A.
Partek Genomics Suite version 7.18	Partek Inc.	N.A.
nSolver version 4.0	NanoString Inc.	N.A.