Table 3.
Factors Associated With Carriage of Multidrug-Resistant Gram-Negative Bacteria in Neonates Admitted to Neonatal Intensive Care Unitsa
| Characteristic | MDR GN Present [n = 113] | Crude Odds Ratio [95% CI] | P Value | Adjusted Odds Ratio [95% CI] | P Value | |
|---|---|---|---|---|---|---|
| Admitting weight (grams) | ≥2500 | 47 [41.6] | 1.00 | |||
| 1500–2499 | 35 [31.0] | 1.06 [0.58–1.93] | .854 | |||
| 1001–1499 | 24 [21.2] | 1.31 [0.65–2.66] | .448 | |||
| ≤1000 | 7 [6.] | 4.02 [0.80–20.31] | .092 | |||
| Duration of stay before sample collection (days) | 9.0 [4.0–22.0] | 1.10 [1.05–1.14] | <.001 | 1.04 [1.01–1.07] | .023 | |
| Age of mother (years) | 29.0 [24.0–35.0] | 0.97 [0.93–1.01] | .152 | |||
| Parity | 1.0 [1.0–3.0] | 0.83 [0.67–1.03] | .092 | |||
| Sex | Male | 52 [46.0] | 0.68 [0.40–1.16] | .159 | ||
| Type of delivery | Caesarean section | 58 [51.3] | 0.78 [0.46–1.32] | .350 | ||
| Type of gestation | Preterm | 72 [64.9] | 1.51 [0.88–2.60] | 0.133 | ||
| Prolonged PROMb | Yes | 9 [10.4] | 3.46 [0.72–16.62] | .121 | ||
| Antibiotic Use | Yes | 92 [81.4] | 15.00 [7.87–28.57] | <.001 | 11.08 [5.54–22.15] | <.001 |
Abbreviations: CI, confidence interval; GN, Gram negative; MDR, multidrug-resistant; PROM, premature rupture of membranes.
aData are presented as medians with interquartile ranges and n/N (%) where appropriate. Significant variables are presented in bold.
bStatistical level of significance set at P < .05.