Table 4.
Factors Associated With Carriage of Third-Generation Cephalosporin-Resistant Bacteria in Neonates Admitted at Neonatal Intensive Care Unitsa
| Characteristic | 3rd-Gen Present n = 105 | Crude Odds Ratio [95% CI] | P Value | Adjusted Odds Ratio [95% CI] | P Value | |
|---|---|---|---|---|---|---|
| Admitting weight (g) | ≥2500 | 44 [41.9] | 1.00 | |||
| 1500–2499 | 32 [30.5] | 1.01 [0.55–1.86] | .972 | |||
| 1001–1499 | 22 [21.0] | 1.24 [0.61–2.51] | .551 | |||
| ≤1000 | 7 [6.7] | 4.53 [0.90–22.91] | .067 | |||
| Duration of stay before specimen collection (days) | 9.0 [4.0–22.0] | 1.07 [1.04–1.10] | <.001 | 1.02 [1.01–1.04] | .044 | |
| Age of mother (years) | 29.0 [24.0–35.0] | 0.97 [0.93–1.02] | .205 | |||
| Parity | 1.0 [1.0–3.0] | 0.84 [0.68–1.04] | .111 | |||
| Sex Male | 47 [44.8] | 0.64 [0.38–1.08] | .097 | |||
| Type of delivery | Caesarean section | 55 [52.4] | 0.86 [0.51–1.44] | .566 | 0.95 [0.49–1.83] | .876 |
| Type of gestation | Preterm | 68 [65.4] | 1.54 [0.89–2.65] | .119 | ||
| Prolonged PROMb | Yes | 8 [9.8] | 2.31 [0.57–9.06] | .231 | ||
| Antibiotic use | Yes | 88 [83.8] | 16.05 [8.27–31.13] | <.001 | 12.87 [6.41–25.83] | <.001 |
Abbreviations: CI, confidence interval; GN, Gram negative; MDR, multidrug resistant; PROM, premature rupture of membranes; 3rd-Gen, third-generation cephalosporin.
aData are presented as medians with interquartile ranges and N (%) where appropriate. Significant variables are presented in boldface.
bStatistical level of significance set at P < .05.