Table 6.
Sputum cell differentials at Visit 2 for acute asthma with viral persistence and viral clearance
Viral persistence | Viral clearance | P‐value | |
---|---|---|---|
Acute asthma, virus positive Visit 1, positive Visit 2 | Acute asthma, virus positive Visit 1, negative Visit 2 | ||
n | 15 | 14 | |
Total cell count (×106/mL) | 4.77 (1.89, 5.76) | 2.88 (1.17, 4.68) | 0.327 |
Neutrophils (%) | 34.8 (10.3, 53.5) | 14.3 (9.0, 42.3) | 0.316 |
Neutrophils (×104/mL) | 130.4 (82.0, 200.2) | 111.7 (7.6, 165.9) | 0.462 |
Eosinophils (%) | 1.9 (1, 4.4) | 5.3 (0.3, 15.6) | 0.303 |
Eosinophils (×104/mL) | 5.9 (0, 7.3) | 3.3 (0, 40.8) | 0.967 |
Macrophages (%) | 57.0 (43.3, 68.3) | 64.6 (42.3, 83.9) | 0.601 |
Macrophages (×104/mL) | 255.5 (81.7, 431.9) | 100.3 (78.2, 269.9) | 0.414 |
Lymphocytes (%) | 0.8 (0, 1.9) | 0.5 (0, 3.5) | 0.930 |
Lymphocytes (×104/mL) | 3.0 (0, 7.2) | 1.2 (0, 3.5) | 0.481 |
Columnar epithelial cells (%) | 0.5 (0.3, 2.5) | 0.6 (0, 1.2) | 0.343 |
Columnar epithelial cells (×104/mL) | 4.0 (1.7, 10.9) | 3.1 (0, 3.4) | 0.151 |
Squamous contamination (%) | 8.3 (3.2, 25.0) | 3.3 (0.7, 12.0) | 0.106 |
Results are median (IQR), Wilcoxon rank sum test.