. Author manuscript; available in PMC: 2021 Feb 1.

Published in final edited form as: J Autoimmun. 2019 Oct 31;107:102354. doi: 10.1016/j.jaut.2019.102354

Table 2.

Alpha diversity in healthy controls and anti-Ro+ mothers of neonatal lupus children.

T axonomic Level	Healthy Controls (N=7) H (e^H)	Asym/UAS^* (N=9) H (e^H)	SS/SLE (N=16) H (e^H)	P-value¹ Healthy Controls vs. All RRNL	P-value² Healthy Controls vs. Asym/UAS vs. SS/SLE	P-value¹ Asym/UAS vs. SS/SLE
Phylum	1.51±0 11 (4.53)	1.34±0.22 (3.82)	1.29±0.23 (3.63)	0.024	0.068	0.562
Class	2.07±0.12 (7.92)	1.91±0.24 (6.75)	1.87±0.22 (6.49)	0.053	0.146	0.709
Order	2.30±0.08 (9.97)	2.08±0.27 (8.00)	2.06±0.20 (7.85)	0.011	0.042	0.863
Family	2.67±0.13 (14.44)	2.36±0.30 (10.59)	2.34±0.20 (10.38)	0.001	0.006	0.796
Genus	3.05±0.19 (21.11)	2.71±0.41 (15.03)	2.71±0.28 (15.03)	0.011	0.043	0.968
Species	3.14±0.28 (23.10)	2.94±0.47 (18.92)	2.87±0.30 (17.64)	0.110	0.257	0.663

Results reported: mean ± standard deviation of the Shannon entropy-based diversity index (H) and the corresponding effective number of elements (exp(H)).

Asym/UAS represents asymptomatic and undifferentiated autoimmune syndrome (UAS major and minor) anti-Ro⁺ neonatal lupus mothers in the RRNL.

P-value for two group comparison using a t-test.

P-value based on all three groups using analysis of variance with ordinal alternative reflecting clinical severity.