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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: J Allergy Clin Immunol. 2019 Dec 12;145(4):1219–1230. doi: 10.1016/j.jaci.2019.10.040

Fig. 3. Gene ontology processes for peanut severity genes encompass major immunemediated pathways.

Fig. 3.

(A) Top twenty gene ontology (GO) enrichment terms associated with peanut severity genes (FDR≤0.05), ranked by fold-enrichment. (B) Clustering of GO terms associated with peanut severity genes (FDR≤0.05) by REVIGO17, with box size inversely corresponding to P-value for association. Bold-faced terms indicate higher order GO processes. (C) Top twenty GO terms for peanut severity genes (ranked by fold-enrichment) that were upregulated with increasing reaction severity (FDR≤0.05). (D) Clustering of GO terms for upregulated peanut severity genes (FDR≤0.05) by REVIGO17, with box size inversely corresponding to P-value of association. Bold-faced terms are for higher order GO processes.