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. 2020 Apr 28;2020(4):CD013594. doi: 10.1002/14651858.CD013594

Pasqualotto 2019.

Study name Randomized Trial of Liposomal Amphotericin B for Histoplasmosis in AIDS Patients
Methods Prospective randomized non‐comparative multicenter open label trial of induction therapy with LAmB for DH in AIDS patients
Participants The sample size planned is 99 patients of both sexes, older than 18 years
Interventions three study arms:
(i) single IV dose of 10 mg/kg of L‐AmB;
(ii) single IV dose of 10 mg/kg of L‐AmB on day 1, followed by 5 mg/kg of L‐AmB on day 3;
(iii) IV dose of 3 mg/kg of L‐AmB for 2 weeks.
Outcomes Primary Outcome Measures
  1. Clinical response

  2. Weight stability

  3. Blood Pressure

  4. Blood oxygen level

Starting date Not yet recruiting
Contact information Alessandro C. Pasqualotto. acpasqualotto@hotmail.com
Notes