Table 3.

Variables Significantly Associated With Treatment Failure in Logistic Regression Analyses^a

Variable	OR	95% CI	P
Univariate logistic regression analysis
Transferred from another hospital	7.1	1.2–43.1	.033c
Hepatomegaly	13.2	2.0–85.8	.007c
Severe hepatitisb	24	3.2–177.4	.002c
Bilirubin total (mg/dL)	106.6	2.2–5191.9	.019c
Chloramphenicol use during admission	20	2.1–192.7	.010c
Multivariate logistic regression analysisa
Transferred from another hospital	2.7	0.2–29.1	.420
Severe hepatitis	13.1	1.4–119.9	.023c
Chloramphenicol use during admission	7.6	0.6–102.7	.128

Abbreviations: CI, confidence interval; OR, odds ratio.

^aVariables included in the multivariate logistic regression analysis limited to “transferred from another hospital,” “chloramphenicol use during admission,” and “severe hepatitis” as the representative hepatic variable to minimize the risk of multicollinearity. Odds ratio for the multivariate log regression analysis is adjusted OR.

^bDefined as an aspartate aminotransferase or alanine aminotransferase level of ≥5 times the upper limits of normal.

^cStatistically significant result.