Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A classic view of EnvZ/OmpR regulation of outer membrane porins in response to osmotic or acid shifts. At low osmolality and neutral pH, OmpF is the major porin in the outer membrane. At high osmolality, ompF transcription is repressed and OmpC becomes the predominant porin. EnvZ autophosphorylation is stimulated by increasing osmolality, driving phosphotransfer to OmpR, dimerization, and high-affinity binding to DNA.
